Biological reagent activity is highly temperature-sensitive; even brief cold chain breaks can cause >20% activity loss. Based on serving 40+ countries, Zechin Bio has developed a 4-stage temperature control strategy.

Stage 1: Factory temperature (-20°C / +4°C)

After filling in the GMP cleanroom, all active products are immediately transferred to -20°C freezers or +4°C cold rooms. Each zone has dual temperature recorders sampling every 5 min, with SMS alerts on anomalies.

Stage 2: Packaging (dry ice + insulated box)

Based on transit time and destination, use 5 kg / 10 kg dry ice with EPS insulated boxes (wall thickness ≥ 30 mm). Verified: in summer 48h transit, internal box temperature stays below -15°C; in winter, dry ice can be reduced to save cost.

Stage 3: International transit (DHL / SF Cold Chain)

International segments use DHL Medical Express (with active temperature data logger); domestic use SF Cold Chain. Customers can view real-time temperature curves on the waybill tracking page. Destinations with >72h transit are auto-upgraded to air cold chain.

Stage 4: Last-mile delivery (intra-city express / self-pickup)

Upon arrival, prefer intra-city cold chain couriers (delivery within 2h); for remote areas, customers can self-pickup at airport cold storage with ID. All deliveries include a temperature record PDF, usable as quality traceability evidence.

For questions on historical order temperature data, contact your sales engineer for the full cold chain record (default 5-year retention).